DIVERSITY IN THE HLA-I RECOGNITION OF HLA-F MONOCLONAL ANTIBODIES: HLA-F OR HLA-IB MONOSPECIFIC, HLA-E OR HLA-G BISPECIFIC ANTIBODIES WITH OR WITHOUT HLA-IA REACTIVITY

Previous investigators have used various anti-HLA-F monoclonal antibodies (mAbs) to demonstrate that the tissue distribution of HLA-F is highly restricted.Notably, these mAbs differed in their immunodiagnostic capabilities.Specifically, mAbs Fpep1.1 and FG1 detected HLA-F intracellularly in B cells but not on the cell surface, whereas mAb 3D11 dete

Functional Apis mellifera honey bee colonies rely on collaborative brood care typically performed by nurse 4 Piece Modular Sectional bees with well-developed hypopharyngeal glands (HPGs).Neonicotinoids, widely used insecticides, have been shown to negatively affect HPG development when worker bees were exposed to field-realistic concentrations eith

Jawed vertebrates possess two distinct groups of muscles in the trunk (epaxial and hypaxial muscles) primarily defined by the pattern of motor innervation from the spinal cord.Of these, the hypaxial group includes muscles with highly differentiated morphology and function, such as the muscles associated with paired limbs, shoulder girdles and tongu

BACKGROUND: The aging related decline of heat shock factor-1 (HSF1) signaling may be causally related to protein aggregation diseases.To model such disease, we tried to cripple HSF1 signaling in the Xenopus tadpole.RESULTS: Over-expression of heat shock factor binding protein-1 did not inhibit the heat shock response in Xenopus.RNAi against HSF1 mR